Mesenchyme-mediated effect of dexamethasone on laminin in cocultures of embryonic gut epithelial cells and mesenchyme-derived cells

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Mesenchyme-mediated effect of dexamethasone on laminin in cocultures of embryonic gut epithelial cells and mesenchyme-derived cells.

Previous studies have shown that glucocorticoids accelerate intestinal maturation and that this process is mediated by the mesenchymal cells. The possible involvement of laminin (LN), a basement membrane component, in this mesenchymal mediation has been analyzed. For this purpose, the influence of dexamethasone (DX) on the synthesis of LN, its chain composition and its cellular distribution has...

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The embryonic mammary rudiment of the mouse re sponds to testosterone with the formation of a condensa tion of mesenchymal cells around the gland bud and subsequent necrosis of the gland epithelium. Experimen tal combinations of epithelium and mesenchyme of this rudiment, by taking advantage of the androgen-insensitive mutant (Tfm, "testicular feminization"), have shown that the hormone acts di...

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Metanephric mesenchyme contains embryonic renal stem cells.

Renal epithelial cells derive from either cells of the metanephric mesenchyme or ureteric bud cells, but the origin of other renal cells is unclear. To test whether metanephric mesenchymal cells generate cells other than epithelial, we examined the developmental potential of a metanephric mesenchymal cell line (7.1.1 cells) and of primary cultures of metanephric mesenchymal cells. 7.1.1 Cells e...

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ژورنال

عنوان ژورنال: Journal of Cell Science

سال: 1992

ISSN: 1477-9137,0021-9533

DOI: 10.1242/jcs.101.1.161